Fowl adenovirus serotype 4 (FAdV) is highly pathogenic and lethal to chickens, especially broilers, which has emerged as one of the most important economic losses for the poultry industry in the past few years。
The more virulent strains (usually type 8 adenovirus) cause a disease called 'epidemic keratoconjunctivitis'. The more mild strains cause pharyngoconjunctival fever. Epidemic keratoconjunctivitis. The virus is transmitted from eye to eye by infected droplets or direct contact.
Fowl adenovirus serotype 11 (FAdV-11) is one of the primary causative agents of inclusion body hepatitis (IBH), which causes substantial economic losses in the world poultry industry.