Clinical use and compatibility of enrofloxacin

As long as pigs have been raised for a year, I believe that everyone is not unfamiliar with enrofloxacin. However, it is understood that many people are not very clear about its use and precautions, and the loss caused by improper clinical use is not uncommon, so today I make an introduction to this, I hope to help you.

Enrofloxacin is used for the prevention and control of 6 diseases

1. Bacterial respiratory diseases: infectious pleuropneumonia, hemophilus parasuis, swine pulmonary disease, streptococcus, parasuis and other diseases; 2. Digestive tract diseases: Colibacillosis (piglet yellow and white dysentery, edema disease), salmonellosis, treponema dysenteriae, leptospira. 3. Genitourinary system: urethritis, cystitis; Sow mastities-metritis-agalactia syndrome; 4. Skin diseases: exudative dermatitis, necrotic bacillus, etc.; 5. Bacterial infections secondary to viral diseases: such as paraswine, streptococcal disease, erythrosomiasis, etc.; 6. various mycoplasma diseases: swine asthma, swine synovial mycoplasma infection, nasal mycoplasma infection.

Clinical use of enrofloxacin

1. pig respiratory disease and intestinal disease piglets often appear cough and diarrhea after weaning, most of which are caused by diseases such as parapig and chest transmission, enrofloxacin has a strong killing effect on these germs, the specific program: After weaning, 10% enrofloxacin is added to 1 kg per ton of feed for 7 days. If the pig farm has a history of torus or other viruses, it can be combined with Astragalus, Fuzheng Jiedu powder or Qingwen Xuedu powder. 2. For joint enlargement or septicemia caused by streptococcus and paraswine, Enrofloxacin injection, amoxicillin + amoxicillin point intramuscular injection was used once a day for 3 days. 3. for the treatment of swine asthma add 10% enrofloxacin 1kg per ton of feed, 10% doxycycline hydrochloride 1kg treatment 7-10 days, has a good effect. 4. Prevention of infectious pleuropneumonia and swine lung disease in fattening pigs by adding 10% enrofloxacin 1 kg and 10% flufenicol 1 kg per ton of feed for 7 days. 5. For the prevention and treatment of metritis in sows, add 1kg each of 10% enrofloxacin and 10% Daqan-Lincomycin per ton of feed; Enrofloxacin is intramuscularly administered 2.5 mg per kilogram of body weight. 6. pig exudative dermatitis treatment with 0.1% potassium permanganoate water (warm water) or 3% hydrogen peroxide, clean the sick pig crusts, exudates, clean and apply waste oil and penicillin mixture, once a day, 2-3 times. Intramuscular injection of 10% Enrofloxacin injection + ceftiofur for injection, once a day, 2-3 times.

Enrofloxacin in combination

1. In order to avoid the generation of drug resistance and improve its efficacy, can be used in combination, enrofloxacin and β-lactam antibiotics (such as: amoxicillin, penicillin), aminoglycoside antibiotics (gentamicin, butanicana, neomycin, etc.) and tetracycline (doxycycline, oxytetracycline) combined with additive or synergistic effect. For example, enrofloxacin injection combined with amoxicillin powder needle can improve its curative effect and expand its antibacterial spectrum. 2. Enrofloxacin + amoxicillin + Fuzheng Jidoxing powder mix administration program plays a good role in the prevention and treatment of bacterial diseases secondary to swine viral diseases. 3. with the content of 2.5% enrofloxacin injection and 10% kanamycin sulfate injection (according to 15 mg/kg), once a day, continuous use for 3 days, has a good therapeutic effect on pig panting disease.

Precautions for use

1. Enrofloxacin palatability is poor, it is not appropriate to drink water administration, oral administration to pigs must be wrapped Enrofloxacin, otherwise it will cause waste, pigs do not eat. 2. do not single long-term drug use. It is recommended to use it alternately with other drugs or in combination with other drugs to reduce the generation of resistance. 3. the dose is prone to side effects. Enrofloxacin is contraindicated in pigs sensitive to enrofloxacin (especially early age piglets), and 1-2 pigs should be tested and the dosage should be strictly controlled before the administration of the drug to a large group of young pigs. 4. pay attention to the feeding object. Use with caution for young animals, not for pregnant sows and nursing sows. 5. Enrofloxacin has antagonistic effect with macrolide antibiotics and flufenicol.