Novel Duck reovirus (NDRV) is an ongoing non-enveloped virus with ten double-stranded RNA genome segments that belong to the genus Orthoreovirus, in the family Reoviridae. NDRV-associated spleen swelling, and necrosis disease have caused considerable economic losses to the waterfowl industry worldwide.
For both NDRV outbreaks, most diseased ducklings were characterized by diarrhea, lethargy, increased eye discharge, loss of appetite, stunted growth, and paralysis. Among the organs collected from the dead ducklings in both cases, the predominant histologic lesions are located in the liver and spleen.