Coccidiosis is an intestinal tract infection caused by a single-celled organism (protozoa) called coccidia. Coccidiosis typically refers to gastrointestinal infections with the Isospora species (sometimes called Cystoisospora) of coccidia, though other species can be found.

Coccidiosis is caused by protozoan parasites from the genus Eimeria. These parasites are host-specific, and many species occupy a specific segment of the intestinal tract. Coccidiosis may be one of the most common diseases affecting small flocks around the world, causing loss in performance and even mortality.

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Fungal growth in feed can decrease its quality substantially. As the molds thrive in feed, it can consume majority of fat, protein, carbohydrate and even mineral elements, leading subsequently to stuff discolorations, heating, mustiness and biochemical transformations, yielding to the accumulation of toxic substances in most cases. The presence of growing molds produce mycotoxins in feedstuff and decreases feed intake, and feed efficiency, while increasing the risk of infection and reproduction disability.

All animals need to receive a nutritious diet in order to maintain good health and production. In the wild, animals consume a wide variety of feed ingredients. Today the nutrient requirements of farm animals and the nutrients provided by different feed ingredients are well understood. Diets for poultry generally consist of cereal grain (mostly corn in the U.S., but also wheat, barley, sorghum, and others are used elsewhere) and a protein source (most commonly soybean meal in the U.S. but there are also several animal and plant protein sources).The nutritional quality of a feed also depends on a variety of other factors, including feed presentation, microbial contamination, the content of antinutritional factors, digestibility, palatability, and intestinal healthfulness. A variety of feed additives are available to deal with these issues.

Fat is often added to poultry diets to increase the energy content, this is especially the case in high density broiler diets. In addition, if fish meal is used, it is high in fat. To help keep feed from going bad, which is common in high fat products, antioxidants are commonly added to the diet. Compounds with antioxidant properties include ethoxyquin, butylhydroxytoluene (BHT), butylhydroxyanisole (BHA), vitamin C, and vitamin E.