List of Manufacturers and Suppliers for 400mg Norfloxacin Tablets in the Pharmaceutical Industry

Overview of Norfloxacin 400 mg Tablets and Their Manufacturers

Norfloxacin, a fluoroquinolone antibiotic, is commonly used to treat bacterial infections in adults. It is particularly effective against infections of the urinary tract, as well as for certain gastrointestinal and respiratory infections. Norfloxacin is marketed in various forms, with the most prevalent being the 400 mg tablet. Understanding the manufacturers of Norfloxacin tablets is crucial for healthcare professionals and patients alike, as it affects the accessibility, quality, and efficacy of the medication.

How Norfloxacin Works

Norfloxacin functions by inhibiting the bacterial DNA gyrase and topoisomerase IV enzymes, which are necessary for the replication and repair of bacterial DNA. By blocking these enzymes, Norfloxacin effectively halts bacterial growth and reproduction, ultimately leading to the eradication of the infection. This mechanism of action, combined with the drug's broad spectrum of activity against gram-negative bacteria and some gram-positive organisms, makes it a valuable option in treating uncomplicated urinary tract infections (UTIs) and certain other bacterial infections.

Importance of Manufacturers

The production of Norfloxacin tablets, including the 400 mg dosage form, is carried out by various pharmaceutical companies worldwide. The manufacturers play a pivotal role in ensuring the consistency, quality, and availability of the medication. Factors such as adherence to Good Manufacturing Practices (GMP), rigorous quality control measures, and regulatory compliance are essential for the production process.

Leading Manufacturers of Norfloxacin Tablets

Several multinational and local pharmaceutical companies manufacture Norfloxacin 400 mg tablets. Some of the notable manufacturers include

1. Bristol-Myers Squibb One of the pioneers in the development of Norfloxacin, Bristol-Myers Squibb has contributed significantly to its formulation and distribution. Their branding and compliance with high manufacturing standards have established them as a trusted source for healthcare providers.

2. Cipla An Indian multinational pharmaceutical company, Cipla is known for producing a wide range of medications, including generics like Norfloxacin. Their focus on affordability has made Norfloxacin accessible in many markets.

3. Mylan Mylan, now part of Viatris, manufactures Norfloxacin among a large portfolio of generic drugs. They emphasize extensive research and development to ensure efficacy and safety.

4. Teva Pharmaceuticals Known for its commitment to quality, Teva offers a variety of formulations of Norfloxacin. They leverage their extensive distribution networks to supply the medication globally.

5. Aurobindo Pharma Another significant player in the generic drug market, Aurobindo Pharma produces Norfloxacin tablets, facilitating access to effective treatment options for bacterial infections.

Quality Control and Regulatory Considerations

The production of Norfloxacin, like all pharmaceuticals, is subject to rigorous quality control measures. Regulatory bodies such as the Food and Drug Administration (FDA) in the United States and the European Medicines Agency (EMA) in Europe ensure that manufacturers adhere to strict guidelines. These regulations cover all aspects of drug production, from raw material sourcing to final packaging, ensuring that the medications are safe for public use.

Conclusion

Norfloxacin 400 mg tablets are an essential part of the antibiotic arsenal used to combat bacterial infections, particularly those affecting the urinary tract. The manufacturers behind this medication play a crucial role in maintaining its quality and accessibility to patients worldwide. As with any medication, healthcare providers must remain informed about the various options available and the reputations of manufacturers to ensure optimal treatment outcomes. The ongoing collaboration between manufacturers, regulatory authorities, and healthcare professionals is key to advancing effective antibiotic therapies.